• Sandra L. Ibáñez-Calero Universidad Privada Boliviana
  • Kelly E. Loayza Afonso Universidad Privada Boliviana



Palabras clave:

Zongo Valley, Antioxidant Activity, Photo-Protector Property, UV-A and/or UV-B Absorption, Distichia muscoides, Souroubea fragilis, Brachyotum microdon, Monnina bridgesii, Baccharis pentlandii, Thibaudia crenulata, Siphocampylus tupaeformis


Eleven plants were collected at the Zongo Valley to evaluate their antioxidant and photo-protector properties. In this paper we report a strong correlation between high antioxidant activity and strong UV-A and/or UV-B absorptions. The most active species, tested at 10µg/ml with the DPPH assay, were Fuchsia boliviana (leaves), Baccharis pentlandii (flowers), Rubus floribundus (fruits), Fuchsia boliviana (flowers and fruits) and Brachyotum microdon (flowers). All the mentioned species have important UV- B and/or UV-A absorptions. This DPPH/UV technique could be used to preliminary screen vegetable samples and to select those with DPPH values above 83% and strong UV-A and/or UV-B absorptions. The chosen samples can then be evaluated with other more expensive in vitro assay (TEAC, ABTS or FRAP) to finally confirm their activities with the in vivo test. To our knowledge, this is the first time that the antioxidant properties of Distichia muscoides, Souroubea fragilis, Brachyotum microdon, Monnina bridgesii, Baccharis pentlandii, Thibaudia crenulata, Siphocampylus tupaeformis, Cobaea scandens, Fuchsia boliviana and Rubus floribundus are reported. In addition, this is the first time that Siphocampylus tupaeformis and Thibaudia crenulata are presented in a publication as well as the study of their photo-protector and antioxidant properties.


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Afiliación del autor/a

Sandra L. Ibáñez-Calero, Universidad Privada Boliviana

Centro de Investigaciones Fitoquímicas (CIF)


R. Szymanska, P. Pospisil and J. Kruk, "Plant-Derived Antioxidants in Disease Prevention," Oxidative Medicine and Cellular Logevity , no. Doi: 10.1155/2018/2068370, 2018.

P. Rajendrana, N. Nandakumar, T. Rengarajan, R. Palaniswamid, E. N. Gnanadhas, U. Lakshminarasaiah, J. Gopasb and I. Nishigakia, "Antioxidant and Human Diseases," Clinica Chimica Acta, vol. 436, pp. 332-347, 2014.

K. Rahman, "Studies on free radicals, antioxidants, and cofactors," Clin Interv Aging, , vol. 2, p. 219–236, 2007.

A. M. Pisoschi, A. Pop, C. Cimpeanu and G. Predoi, "Antioxidant Capacity Determination in Plants and Plant-Derived Products: A Review," Oxid Med Cell Longev, no. Doi: 10.1155/2016/9130976., 2016.

E. A. Shalaby and S. M. M. Shanab, "Antioxidant Compounds, Assays of Determination and Mode of Action," African Journal of Pharmacy and Pharmacology, vol. 7, pp. 528-539, 2013.

D. M. Kasote, S. S. Katyare, M. V. Hegde and H. Bae, "Significance of Antioxidant Potential of Plants and its Relevance to Therapeutic Applications," Int. J. Biol. Sci., vol. 11, pp. 982- 991, 2015.

T. Ortuño, Estudio palinológico en un gradiente altitudinal en el valle de Zongo. Tesis de licenciatura en Biología, La Paz- Bolivia: UMSA, 2000.

M. Baudoin, Historia natural de un valle de los Andes, La Paz: Instituto de Ecología-UMSA, 1991.

M. Joyeaux, A. Lobstein, R. Anton and F. Mortier, "Comparative antilipoperoxidant, antinecrotic and scavenging properties of terpenes and biflavones from Ginkgo and some flavonoids," Planta Med. , vol. 61, pp. 126-129, 1995.

H. Balslev, Flowering Plant. Monocotyledons, Springer, 1998.

P. Gonzáles, M. Suni, R. Deanna, M. A. Scaldaferro, E. Castañeda, D. W. Ramirez, N. Valencia and A. Cano, "Reproductive biology and cytogenetics of Distichia muscoides (Juncaceae)," Boletín de la Sociedad Argentina de Botánica, vol. 51, pp. 123-133, 2016.

S. Loza Herrera, R. I. Meneses and F. Anthelme, "Comunidades vegetales de los bofedales de la Cordillera Real (Bolivia) bajo el calentamiento global / Plant communities of high-Andean wetlands of the Cordillera Real (Bolivia) in the face of global warming," Ecología en Bolivia, vol. 50, pp. 39-56, 2015.

S. L. Ibáñez-Calero, K. E. Loayza, E. L. Yapu, J. Lizarazu, R. Zeballos and T. Solares, "A Screening of Natural Colorants with probable antioxidant and/or photo-protector activities," Investigacion y Desarrollo, vol. 16, pp. 5-24, 2016.

M. Abad, A. Bessa, B. Ballarin, O. Aragón, E. Gonzales and P. Bermejo, "Anti-inflammatory activity of four Bolivian Baccharis species (Compositae)," J. Ethnopharmacol., vol. 103, pp. 338-344, 2006.

S. L. Ibáñez-Calero, Application du test d’inhibition de la biocristallisation de l´heme a la caracterisation de composes antipaludiques isoles de la flore de Bolivie. Ph.D. thesis, Toulouse- France: Universite Paul Sabatier, 2005.

S. Tarqui, Y. Flores and G. Almanza, "Polyoxygenated flavonoids from Baccharis pentlandii," Revista Boliviana de Química, vol. 29, pp. 10- 14, 2012.

S. L. Ibáñez-Calero, V. Jullian, S. C. d. M. L. R. Chevalley, J. Bravo, A. Gimenez and M. Sauvain, "Application of Ferriprotoporphyrin Biocrystallization Inhibition Test to Find Antiplasmodial Compounds in the Flora of the Zongo Valley- Bolivia," Revista Boliviana de Química, vol. 29, pp. 71-79, 2012.

F. R. Pérez Azahuanche, J. C. Guerrero Hurtado, Z. M. Ortiz Rubio, F. Rodríguez Ávalos and G. León Aponte, "Análisis fitoquímico preliminar y evaluación de la actividad hipoglucemiante de Rubus loribundus Kunth (Rosaceae) "zarzamora"," Arnaldoa, vol. 21, pp. 391- 401, 2014.

J. C. Guerrero Hurtado, G. León Aponte, F. R. Pérez Azahuanche, F. Rodríguez Ávalos and Z. M. Ortiz Rubio, "Aislamiento y caracterización estructural de los principios activos hipoglucemiantes de Rubus floribundus Kunth (Rosaceae) “zarzamora"," Arnaldoa, vol. 22, pp. 381- 394, 2015.

C. V. Pérez Rodríguez and F. R. Pérez Azahuanche, "La temperatura en las propiedades fisicoquímicas, contenido de vitamina C y recuento de mohos y levaduras del mesocarpio de “zarzamora” Rubus floribundus kunth (Rosaceae)," Arnaldoa, vol. 26, pp. 297-304, 2019.

I. H. Castillo Vera, Importancia cultural de la flora silvestre utilizada por los pobladores del caserío de Cabrero en la microcuenca Quebrada Honda (Cajabamba, Cajamarca, Perú) TESIS Para optar el Grado Académico de Magíster en Botánica Tropical con mención en Etnobotánica, Lima-Peru: Universidad Nacional Mayor de San Marcos Universidad del Perú, 2018.

M. Wegiera, H. Smolarz and Bogucka-Kocka, "Rumex L. species induce apoptosis in 1301, EOL-1 and H-9 cell lines," A. Acta Pol Pharm., vol. 69, pp. 487-499, 2012.

N. C. Institute, "PDQ Cancer Information Summaries [Internet]. US. February 3, 2014.," US, USA, 2014.

Ł. Łuczaj and W. Szymański, "Wild vascular plants gathered for consumption in the Polish countryside: a review," J Ethnobiol Ethnomed. , vol. 15, pp. 3-17, 2007.

Ł. Łuczaj, P. Köhler, E. Pirożnikow, M. Graniszewska, A. Pieroni and T. Gervasi, "Wild edible plants of Belarus: from Rostafiński’s questionnaire of 1883 to the present," J Ethnobiol Ethnomed, no. doi: 10.1186/1746-4269-9-21, 2013.

S. Kültür, "An ethnobotanical study of Kırklareli (Turkey)," Phytologia Balcanica, vol. 14, p. 279 –289, 2008.

T. Özen, "Antioxidant activity of wild edible plants in the Black Sea Region of Turkey," Grasas y aceites, no. search.ebscohost.com. , 2010.

M. S. Amiri, M. R. Joharchi and M. E. TaghavizadehYazdi, "Ethno-Medicinal Plants Used to Cure Jaundice by Traditional Healers of Mashhad, Iran," Iranian Journal of Pharmaceutical Research, vol. 13, pp. 157-162, 2014.

D. Tewari, A. Mocan, E. D. Parvanov, A. N. Sah, S. M. Nabavi, L. Huminiecki, Z. F. Ma, Y. Y. Lee, J. O. Horbańczuk and A. G. Atanasov, "Ethnopharmacological Approaches for Therapy of Jaundice: Part I," Front Pharmacol., no. doi: 10.3389/fphar.2017.0051, 2017.

M. S. Amiri, M. R. Joharchi and M. E. TaghavizadehYazdi, "Ethnobotanical investigation of traditional medicinal plants commercialized in the markets of Mashhad, Iran," Avicenna. J Phytomed., vol. 3, no. 3, p. 254–271, 2013.

W. Kipkore, B. Wanjohi, H. Rono and G. Kigen, "A study of the medicinal plants used by the Marakwet Community in Kenya," J. Ethnobiol. Ethnomed., no. doi: 10.1186/1746-4269-10-24, 2014.

A. Pieroni, B. Rexhepi, A. Nedelcheva, A. Hajdari, B. Mustafa, V. Kolosova, K. Cianfaglione and C. L. Quave, "One century later: the folk botanical knowledge of the last remaining Albanians of the upper Reka Valley, Mount Korab, Western Macedonia," J. Ethnobiol. Ethnomed., no. doi: 10.1186/1746-4269-9-22, 2013.

S. Arı, M. Temel, M. Kargıoğlu and M. Konuk, "Ethnobotanical survey of plants used in Afyonkarahisar-Turkey," J. Ethnobiol. Ethnomed., no. doi: 10.1186/s13002-015-0067-6, 2015.

G. Tuttu, G. Abay and S. Yildirimli, "Some Wild Edible Plants of Tosya District (Kastamonu, Turkey)," International Journal of Scientific and Technological Research, vol. 5, no. 3, pp. 129-135, 2019.

A. Vasas, O. Orbán-Gyapai and J. Hohmann, "The genus Rumex: review of traditional uses, phytochemistry and pharmacology," J. Ethnopharmacol., vol. 175, pp. 198- 228, 2015.

C. Lans, "Do recent research studies validate the medicinal plants used in British Columbia, Canada for pet diseases and wild animals taken into temporary care?," Journal of Ethnopharmacology, vol. 236, pp. 366-392, 2019.

D. Ahmed, Q. Mughal, S. Younas and M. Ikram, "Study of phenolic content and urease and alpha-amylase inhibitory activities of methanolic extract of Rumex acetosella roots and its sub-fractions in different solvents," Pak. J. Pharm. Sci., vol. 26, pp. 553-559, 2013, 2013.

N. Zarrin Sarhady, B. Ali Mandegary, S. Fariba, M. Saeedeh and I. Maryam, "Evaluation of the hepatoprotective effects of Rumex acetosella on the carbon tetrachloride-induced hepatotoxicity in rats," Avicenna Journal of Phytomedicine, vol. 5, pp. 134-135, 2015.

S. Fatma Zerrin and C. Hale Seçilmiş, "Determination of Heavy Metals and Nutrient Elements in Some Medicinal Plants Used in Eskişehir," Journal of Natural & Applied Sciences, vol. 19, pp. 83-90, 2015.

O. Rodríguez, R. Célio, F. Aboukhair, A. M. Laurrabaquio, I. O. Tinoco, H. U. Cuevas, M. A. Cruz Suárez, M. A. Cruz Marmolejo and M. C. Reyes, "Prueba cutánea con extractos alergénicos de pólenes y relación con signos clínicos de rinitis alérgica y asma bronquial en Camagüey, Cuba," Revista Vacci Monitor (Vacunología y Temas Afines), vol. 22, pp. 9-13, 2013.

L. Tejeda, Antioxidants in Andean food and meals. PhD Thesis in Food Engineering, Lund: Lund University Publications, 2013.

B. Zengin Kurt, I. Gazioğlu, E. Sevgi and F. Sönmez, "Anticholinesterase, Antioxidant, Antiaflatoxigenic Activities of Ten Edible Wild Plants from Ordu Area, Turkey, Iran," J Pharm Res., vol. 17, no. 3, p. 1047–1056, 2018.

S. Sekhon-Loodu and H. P. Rupasinghe, "Evaluation of antioxidant, antidiabetic and antiobesity potential of selected traditional medicinal plants," Frontiers in nutrition, no. doi.org/10.3389/fnut.2019.00053, 2019.

M. Alikhani Pour, S. Sardari, A. Eslamifar, A. Azhar, M. Rezvani and M. Nazari, "Cheminformatics-Based Anticoagulant Study of Traditionally Used Medicinal Plants," Iran Biomed. J. , vol. 21, no. 6, p. 400–405, 2017.

M. Banga, E. J. Slaa, C. W. P. M. Blom and L. A. C. J. Voesenek, "Ethylene Biosynthesis and Accumulation under Drained and Submerged Conditions (A Comparative Study of Two Rumex Species)," Plant Physiol. , vol. 112, no. 1, p. 229–237, 1996.

I. Khan, A. Bahuguna, M. Krishnan, S. Shukla, H. Lee, S. Min, D. Kyu Choi, Y. Cho, V. K. Bajpai, Y. Suk Huh and S. Chul Kang, "The effect of biogenic manufactured silver nanoparticles on human endothelial cells and zebrafish model," Science of the Total Environment, vol. 679, p. 365–377, 2019.

N. Verma, A. Pratap Singh and C. V. Rao, "Antioxidant mediated ulcer healing potential of hyperin isolated from flowers of rhododendron arboreum in experimental rat," International journal of pharmaceutical sciences and research, vol. 10, no. 3, pp. 1524- 1533, 2019.

S. Q. De Oliveira, F. Dal-Pizzol, J. C. F. Moreira, E. P. Schenkel and G. Gosmann, "Antioxidant activity of Baccharis spicata, Baccharis trimera and Baccharis usterii," Acta Farm. Bonaerense, vol. 23, no. 3, pp. 365-368, 2004.

C. B. De Oliveira, L. N. Comunello, A. Lunardelli, R. H. Amaral, M. G. S. Pires, G. L. Da Silva, V. Manfredini, C. Regla Vargas, S. C. B. Gnoatto, J. R. De Oliveira and G. Gosmann, "Phenolic Enriched Extract of Baccharis trimera Presents Anti-inflammatory and Antioxidant Activities," Molecules, vol. 17, no. 1, pp. 1113-1123, 2012.

S. Q. De Oliveira, F. Dal-Pizzol, G. Gosmann, D. Guillaume, J. C. F. Moreira and E. P. Schenkel, "Antioxidant Activity of Baccharis articulata Extracts: Isolation of a New Compound with Antioxidant Activity," Free Radical Research, vol. 37, no. 5, pp. 555-559, 2003.

B. Da Cruz Pádua, L. D. Silva, J. V. Rossoni Júnior, J. L. Humberto, M. Martins Chaves, M. E. Silva, M. L. Pedrosa and D. Caldeira Costa, "Antioxidant properties of Baccharis trimerain the neutrophils of Fisher rats," Journal of Ethnopharmacology, vol. 129, no. 3, pp. 381-386, 2010.

M. J. Simirgiotis, C. Quispe, J. Bórquez, A. Mocan and B. Sepúlveda, "High resolution metabolite fingerprinting of the resin of Baccharis tola Phil. from the Atacama Desert and its antioxidant capacities," Industrial Crops and Products, vol. 94, pp. 368-375, 2016.

S. M. Sabir, M. L. Athayde, A. A. Boligon and J. B. T. Rocha, "Antioxidant activities and phenolic profile of Baccharis trimera, a commonly used medicinal plant from Brazil," South African Journal of Botany, vol. 113, pp. Pages 318-323, 2017.

J. Mann, Secondary Metabolism, 2nd edition, Oxford: Oxford Science Publications, 1992.



Cómo citar

Ibáñez-Calero, S. L., & Loayza Afonso, K. E. (2019). A SCREENING FOR ANTIOXIDANT SPECIES WITH PHOTO-PROTECTOR ACTIVITIES AT THE ZONGO VALLEY (BOLIVIA). Revista Investigación &Amp; Desarrollo, 19(1). https://doi.org/10.23881/idupbo.019.1-2i